Infradiaphragmatic Hodgkin lymphoma: a large series of patients staged with PET-CT

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TitreInfradiaphragmatic Hodgkin lymphoma: a large series of patients staged with PET-CT
Type de publicationJournal Article
Year of Publication2017
AuteursRossi C, Mounier M, Brice P, Safar V, Nicolas-Virelizier E, Rey P, Stamatoullas-Bastard A, Alcantara M, Chauchet A, Reboursiere E, Filliatre L, Perrot A, Garciaz S, Salles G, Coiffier B, Ghesquieres H, Casasnovas R-O
JournalONCOTARGET
Volume8
Pagination85110-85119
Date PublishedOCT 17
Type of ArticleArticle
Mots-clésHodgkin lymphoma, infradiaphragmatic, radiotherapy
Résumé

{Introduction: Infradiaphragmatic Hodgkin Lymphoma (IDHL) accounts for 3-11% of adult cases of stage I-II Hodgkin Lymphoma and the treatment strategy in IDHL is still heterogeneous. All previous published studies were conducted before the PET-CT era. PET may provide a more accurate evaluation of IDHL stage. The aim of this study was to analyze the clinical and biological characteristics of IDHL patients staged by CT scan or PET-CT in eight French hematology departments and their impact on outcomes in these patients. Methods: Baseline clinical and biological data and outcomes in patients with a first diagnosis of stage I-II IDHL treated with ABVD +/-radiotherapy were retrospectively collected. Results: Among the 99 patients included, 65 (66%) were staged with PET-CT. These patients were older (53 years vs 46 years
DOI10.18632/oncotarget.19389