Cytotoxic glycosides from the roots of Weigela x ``Bristol Ruby''

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TitreCytotoxic glycosides from the roots of Weigela x ``Bristol Ruby''
Type de publicationJournal Article
Year of Publication2019
AuteursNguyen DHung, Mitaine-Offer A-C, Maroso S, Papini A-M, Paululat T, Bellaye P-S, Collin B, Chambin O, Lacaille-Dubois M-A
JournalFITOTERAPIA
Volume137
Pagination104242
Date PublishedSEP
Type of ArticleArticle
ISSN0367-326X
Mots-clésCaprifoliaceae, Cytotoxicity, NMR, Oleanolic acid glycosides, Weigela x ``Bristol Ruby''
Résumé

Seven oleanane-type glycosides were extracted and isolated by various chromatographic methods from the roots of Weigela x ``Bristol Ruby'' (1-7), six previously undescribed (1-6) and a known one (7). Their structures were assigned by spectroscopic analysis mainly 2D NMR and mass spectrometry (ESIMS). Selected triterpenoid glycosides (1-3, 6, 7) displayed a good cytotoxic activity against a mouse colon cancer cell line CT26.

DOI10.1016/j.fitote.2019.104242