New method for the synthesis of 4-aryl-3,4-dihydro-2H-benzo[g]chromene-2,5,10-triones

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TitreNew method for the synthesis of 4-aryl-3,4-dihydro-2H-benzo[g]chromene-2,5,10-triones
Type de publicationJournal Article
Year of Publication2019
AuteursChoura E, Ncir M, Maalej E, Marco-Contelles J, Ismaili L, Chabchoub F
JournalSYNTHETIC COMMUNICATIONS
Volume49
Pagination2834-2839
Date PublishedNOV 2
Type of ArticleArticle
ISSN0039-7911
Mots-clés10-dihydro-4H-benzo[g]chromene-3-carbonitriles, 10-dioxo-5, 10-triones, 2-Amino-4-aryl-5, 4-aryl-3, 4-dihydro-2H-benzo[g]-chromene-2, 5, 88% formic acid, antioxidant activity
Résumé

We report herein a new method for the synthesis of 4-aryl-3,4-dihydro-2H-benzo[g]chromene-2,5,10-triones 4 that proceeds in good yields (74-86%) and mild reaction conditions between readily available 2-amino-4-aryl-5,10-dioxo-5,10-dihydro-4H-benzo[g]chromene-3-carbonitr iles 1, and formic acid (88%), at reflux for 6 h. In addition, we have also studied the antioxidant activities using DPPH and total TAC methods. [GRAPHICS] .

DOI10.1080/00397911.2019.1646286, Early Access Date = {JUL 2019