Associated arterial and venous cerebral manifestations in Behcet's disease

Behcet's disease is a rare multisystemic vasculitis with an etiology that is still unknown. Neurological manifestations may be seen in approximately 5-15% of patients, and both parenchymal and extraparenchymal neurological involvement has been described. When cerebral venous thrombosis (CVT) is the main extraparenchymal manifestation of Behcet's disease, the condition is then dubbed ``angio-Behcet's syndrome''. However, arterial involvement is extremely rare, with only one reported case of vasculo-neuro-Behcet's disease, characterized by both venous and intracranial arterial involvement-until now. This report is of two patients diagnosed with Behcet's disease characterized by the concomitant presence of both cerebral arterial manifestations and CVT. (C) 2018 Elsevier Masson SAS. All rights reserved.