Clinical and microbiological characteristics of cystic fibrosis adults never colonized by Pseudomonas aeruginosa: Analysis of the French CF registry
| Affiliation auteurs | !!!! Error affiliation !!!! |
| Titre | Clinical and microbiological characteristics of cystic fibrosis adults never colonized by Pseudomonas aeruginosa: Analysis of the French CF registry |
| Type de publication | Journal Article |
| Year of Publication | 2019 |
| Auteurs | Vongthilath R, Thiriez BRichaud, Dehillotte C, Lemonnier L, Guillien A, Degano B, Dalphin M-L, Dalphin J-C, Plesiat P |
| Journal | PLOS ONE |
| Volume | 14 |
| Pagination | e0210201 |
| Date Published | JAN 8 |
| Type of Article | Article |
| ISSN | 1932-6203 |
| Résumé | {Pseudomonas aeruginosa is the main cause of chronic airway infection in cystic fibrosis (CF). However, for unclear reasons some patients are never colonized by P. aeruginosa. The objectives of this study were to better define the clinical, genetic, and microbiological characteristics of such a subpopulation and to identify predictive factors of non-colonization with P. aeruginosa. The French CF patient registry 2013-2014 was used to identify CF patients aged >= 20 years. The clinical outcomes, CF Transmembrane conductance Regulator (CFTR) genotypes, and microbiological data of patients reported positive at least once for P. aeruginosa (''Pyo'' group |
| DOI | 10.1371/journal.pone.0210201 |