Lipid-Lowering Drugs Associated With Slower Motor Decline in the Elderly Adults
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Titre | Lipid-Lowering Drugs Associated With Slower Motor Decline in the Elderly Adults |
Type de publication | Journal Article |
Year of Publication | 2014 |
Auteurs | Dumurgier J, Singh-Manoux A, Tavernier B, Tzourio C, Elbaz A |
Journal | JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES |
Volume | 69 |
Pagination | 199-206 |
Date Published | FEB |
Type of Article | Article |
ISSN | 1079-5006 |
Mots-clés | epidemiology, gait, Lipid-lowering drugs, Motor function, Statins |
Résumé | {Background. Vascular risk factors contribute to motor decline in the elderly persons. We investigated the relationship between lipid-lowering drugs (LLDs) use and decline in walking speed (WS) in older adults. Methods. Data on 4,009 community-dwelling men and women, aged >= 65 years at baseline, are drawn from the Dijon (France) center of the Three-City study. ``Fast'' WS was assessed over 6 m at baseline and at 4, 6, 8, and 10 years of follow-up. Mixed linear models were used to determine the relationship between LLDs and change in WS over the follow-up. Results. At baseline, 1,295 (32%) participants used LLDs (statins |
DOI | 10.1093/gerona/glt140 |