Lipid-Lowering Drugs Associated With Slower Motor Decline in the Elderly Adults

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TitreLipid-Lowering Drugs Associated With Slower Motor Decline in the Elderly Adults
Type de publicationJournal Article
Year of Publication2014
AuteursDumurgier J, Singh-Manoux A, Tavernier B, Tzourio C, Elbaz A
JournalJOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
Volume69
Pagination199-206
Date PublishedFEB
Type of ArticleArticle
ISSN1079-5006
Mots-clésepidemiology, gait, Lipid-lowering drugs, Motor function, Statins
Résumé

{Background. Vascular risk factors contribute to motor decline in the elderly persons. We investigated the relationship between lipid-lowering drugs (LLDs) use and decline in walking speed (WS) in older adults. Methods. Data on 4,009 community-dwelling men and women, aged >= 65 years at baseline, are drawn from the Dijon (France) center of the Three-City study. ``Fast'' WS was assessed over 6 m at baseline and at 4, 6, 8, and 10 years of follow-up. Mixed linear models were used to determine the relationship between LLDs and change in WS over the follow-up. Results. At baseline, 1,295 (32%) participants used LLDs (statins

DOI10.1093/gerona/glt140