Long-term outcomes and cardiac surgery in critically ill patients with infective endocarditis

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TitreLong-term outcomes and cardiac surgery in critically ill patients with infective endocarditis
Type de publicationJournal Article
Year of Publication2014
AuteursMirabel M, Sonneville R, Hajage D, Novy E, Tubach F, Vignon P, Perez P, Lavoue S, Kouatchet A, Pajot O, Mekontso-Dessap A, Tonnelier J-M, Bollaert P-E, Frat J-P, Navellou J-C, Hyvernat H, Hssain AAit, Timsit J-F, Megarbane B, Wolff M, Trouillet J-L, Grp ENDOREAStudy
JournalEUROPEAN HEART JOURNAL
Volume35
Pagination1195-U36
Date PublishedMAY
Type of ArticleArticle
ISSN0195-668X
Mots-clésHeart valve disease, Intensive care, Valve surgery
Résumé

{Aims To assess long-term outcomes and the management of critical left-sided infective endocarditis (IE) and evaluate the impact of surgery. Methods and results Among the 198 patients included prospectively for IE across 33 adult intensive care units (ICU) in France from 1 April 2007 to 1 October 2008, 137 (69%) were dead at a median follow-up time of 59.5 months. Characteristics significantly associated with mortality were: Sepsis-related Organ-Failure Assessment (SOFA) score at ICU admission [Hazard ratio (HR), 95% Confidence Interval (CI) of 1.43 (0.79-2.59) for SOFA 5-9; 2.01 (1.05-3.85) for SOFA 10-14; 3.53 (1.75-7.11) for SOFA 15-20; reference category SOFA 0-4; P = 0.003]; prosthetic mechanical valve IE [HR 2.01; 95% CI 1.09-3.69
DOI10.1093/eurheartj/eht303