Tumor microenvironment: regulatory cells and immunosuppressive cytokines
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Titre | Tumor microenvironment: regulatory cells and immunosuppressive cytokines |
Type de publication | Journal Article |
Year of Publication | 2014 |
Auteurs | Bruchard M, Ghiringhelli F |
Journal | M S-MEDECINE SCIENCES |
Volume | 30 |
Pagination | 429–435 |
Date Published | APR |
Type of Article | Review |
ISSN | 0767-0974 |
Résumé | Immunosuppression is a mechanism developed by cancer cells to help them escape the immune system. Immunosuppression involves expansion of various cell types and production of a variety of cytokines. In this review, we explore the duality of three cancer induced cell populations, regulatory T lymphocytes, Th17 lymphocytes and MDSC, and also the pleiotropic effects of several cytokines induced during cancer development. |
DOI | 10.1051/medsci/20143004018 |