Conversion From Belatacept to Another Immunosuppressive Regimen in Maintenance Kidney-Transplantation Patients

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TitreConversion From Belatacept to Another Immunosuppressive Regimen in Maintenance Kidney-Transplantation Patients
Type de publicationJournal Article
Year of Publication2020
AuteursGouin A, Sberro-Soussan R, Courivaud C, Bertrand D, Del Bello A, Darres A, Ducloux D, Legendre C, Kamar N
JournalKIDNEY INTERNATIONAL REPORTS
Volume5
Pagination2195-2201
Date PublishedDEC
Type of ArticleArticle
ISSN2468-0249
Mots-clésbelatacept, calcineurin inhibitor, conversion, donor-specific antibody, kidney function, Safety
Résumé

{Introduction: During the coronavirus disease 2019 (Covid-19) pandemic, several physicians have questioned pursuing belatacept in kidney-transplant patients in order to reduce the risk of nosocomial transmission during the monthly infusion. The effect of the conversion from belatacept to another immunosuppressive regimen is underreported. The aim of the present retrospective study was to assess the effect on kidney function and the clinical outcome of the conversion from belatacept to another regimen. Methods: We have identified 44 maintenance kidney transplantation patients from five French kidney transplantation centers who were converted from belatacept to another regimen either because of a complication (n = 28) or another reason (patients' request or belatacept shortage

DOI10.1016/j.ekir.2020.09.036