Response to Tocilizumab in Rheumatoid Arthritis Is Not Influenced by the Body Mass Index of the Patient

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TitreResponse to Tocilizumab in Rheumatoid Arthritis Is Not Influenced by the Body Mass Index of the Patient
Type de publicationJournal Article
Year of Publication2015
AuteursPers Y-M, Godfrin-Valnet M, Lambert J, Fortunet C, Constant E, Mura T, Pallot-Prades B, Jorgensen C, Maillefert J-F, Marotte H, Wendling D, Gaudin P
JournalJOURNAL OF RHEUMATOLOGY
Volume42
Pagination580-584
Date PublishedAPR
Type of ArticleArticle
ISSN0315-162X
Mots-clésbody mass index, Response, Rheumatoid arthritis, tocilizumab
Résumé

{Objective. To assess the relationship between the body mass index (BMI) and the efficacy of tocilizumab (TCZ) in patients with rheumatoid arthritis (RA). Methods. We conducted a retrospective study in 222 patients with RA followed by 5 centers. The European League Against Rheumatism response was evaluated at 6 months. Univariate and multivariate logistic regressions were performed. Results. No significant association between the BMI and the response to TCZ at 6 months was found after adjustment for potential confounding factors (adjusted OR 0.45, 95% CI 0.16-1.24

DOI10.3899/jrheum.140673