ROTAVIRUS VACCINE VIRUS SHEDDING, VIREMIA AND CLEARANCE IN INFANTS WITH SEVERE COMBINED IMMUNE DEFICIENCY
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Titre | ROTAVIRUS VACCINE VIRUS SHEDDING, VIREMIA AND CLEARANCE IN INFANTS WITH SEVERE COMBINED IMMUNE DEFICIENCY |
Type de publication | Journal Article |
Year of Publication | 2015 |
Auteurs | Kaplon J, Cros G, Ambert-Balay K, Leruez-Ville M, Chomton M, Fremy C, Pothier P, Blanche S |
Journal | PEDIATRIC INFECTIOUS DISEASE JOURNAL |
Volume | 34 |
Pagination | 326-328 |
Date Published | MAR |
Type of Article | Article |
ISSN | 0891-3668 |
Mots-clés | Diarrhea, rotavirus vaccine, SCID, viremia |
Résumé | We report for the first time Rotarix vaccine-acquired rotavirus infections with viremia in 2 infants vaccinated before being diagnosed with severe combined immune deficiency. Monitoring the first infant revealed that persistent rotavirus infection resolved after complete immune reconstitution was achieved by gene therapy. |
DOI | 10.1097/INF.0000000000000560 |