Efficacy and safety of biologics in relapsing polychondritis: a French national multicentre study
| Affiliation auteurs | !!!! Error affiliation !!!! |
| Titre | Efficacy and safety of biologics in relapsing polychondritis: a French national multicentre study |
| Type de publication | Journal Article |
| Year of Publication | 2018 |
| Auteurs | Moulis G, Pugnet G, Costedoat-Chalumeau N, Mathian A, Leroux G, Boutemy J, Espitia O, Bouillet L, Berthier S, Gaultier J-B, Jeandel P-Y, Konate A, Mekinian A, Solau-Gervais E, Terrier B, Wendling D, Andry F, Garnier C, Cathebras P, Arnaud L, Palmaro A, Cacoub P, Amoura Z, Piette J-C, Arlet P, Lapeyre-Mestre M, Sailler L |
| Journal | ANNALS OF THE RHEUMATIC DISEASES |
| Volume | 77 |
| Pagination | 1172-1178 |
| Date Published | AUG |
| Type of Article | Article |
| ISSN | 0003-4967 |
| Résumé | {Objectives To assess the efficacy and the safety of biologics in a cohort of patients with relapsing polychondritis (RP). Methods We conducted a French multicentre retrospective cohort study including patients treated with biologics for RP. Efficacy outcomes were clinical response (partial or complete) and complete response during the first 6 months of exposure, plus daily corticosteroid dose at 6 months. Other outcomes were adverse drug reactions (ADRs), persistence of biologics and factors associated with a response. Results This study included 41 patients exposed to 105 biologics (tumour-necrosis factor (TNF) inhibitors |
| DOI | 10.1136/annrheumdis-2017-212705 |