Long-term efficacy and safety of etravirine-containing regimens in a real-life cohort of treatment-experienced HIV-1-infected patients
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Titre | Long-term efficacy and safety of etravirine-containing regimens in a real-life cohort of treatment-experienced HIV-1-infected patients |
Type de publication | Journal Article |
Year of Publication | 2016 |
Auteurs | Allavena C, Katlama C, Cotte L, Roger PMarie, Delobel P, Cheret A, Duvivier C, Poizot-Martin I, Hoen B, Cabie A, Cheret A, Lahoulou R, Raffi F, Pugliese P, Grp D'AIDSstudy |
Journal | INFECTIOUS DISEASES |
Volume | 48 |
Pagination | 392-398 |
Date Published | MAY 3 |
Type of Article | Article |
ISSN | 2374-4235 |
Mots-clés | etravirine, HIV, NNRTI, Tolerability, virological efficacy |
Résumé | {Objectives Etravirine (ETR) was approved in France in September 2008 and is used in combination with a boosted protease inhibitor (bPI) and other anti-retrovirals (ART) in HIV-infected pre-treated patients. This study aimed to report in a real-life setting the efficacy and tolerability of ETR-based regimens and factors associated with virological response. Methods The study population included all treatment-experienced patients who initiated an ETR-based regimen between September 2008 and July 2013 from the French Dat'AIDS cohort. Analyses were performed in ART-experienced patients starting ETR after virological failure (VF) or as a maintenance therapy (MT), with or without bPI. Results A total of 2006 patients (VF |
DOI | 10.3109/23744235.2015.1133927 |