Fatal acute respiratory distress by Toxoplasma gondii in a toxoplasma seronegative liver transplant recipient

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TitreFatal acute respiratory distress by Toxoplasma gondii in a toxoplasma seronegative liver transplant recipient
Type de publicationJournal Article
Year of Publication2016
AuteursMiltgen G, Paillot J, Vanlemmens C, Di Martino V, Heyd B, Millon L, Bellanger A-P
JournalNEW MICROBIOLOGICA
Volume39
Pagination160-162
Date PublishedAPR
Type of ArticleArticle
ISSN1121-7138
Résumé

The risk of Toxoplasma gondii infection in solid organ transplant recipients is well known but mainly after heart transplantation. We discuss a case of acute respiratory distress caused by Toxoplasma gondii on Day 32 after liver transplantation. The reported case, which is extremely rare, emphasizes how direct examination and Quantitative Polymerase Chain Reaction (QPCR) in broncholaveolar lavage help to diagnose the infection. Given Trimethoprim/Sulfamethoxazole toxicity, systematic prescription of Toxoplasma gondii chemoprophylaxis is not commonly approved in liver transplantation.