Bortezomib and dexamethasone, an original approach for treating multi-refractory warm autoimmune haemolytic anaemia
| Affiliation auteurs | !!!! Error affiliation !!!! |
| Titre | Bortezomib and dexamethasone, an original approach for treating multi-refractory warm autoimmune haemolytic anaemia |
| Type de publication | Journal Article |
| Year of Publication | 2019 |
| Auteurs | Fadlallah J, Michel M, Crickx E, Limal N, Costedoat N, Malphettes M, Fieschi C, Galicier L, Oksenhendler E, Godeau B, Audia S, Mahevas M |
| Journal | BRITISH JOURNAL OF HAEMATOLOGY |
| Volume | 187 |
| Pagination | 124-128 |
| Date Published | OCT |
| Type of Article | Article |
| ISSN | 0007-1048 |
| Mots-clés | auto-immune haemolytic anaemia, bortezomib, refractory |
| Résumé | {We report the off-label use of bortezomib combined with dexamethasone in eight adults with severe and multi-refractory warm auto-immune haemolytic anaemia (wAIHA). After six cycles of induction therapy, 6 of the 8 patients achieved response (3 complete response, 3 response). Response was obtained after a median of 2 (1-4) cycles. After a median follow-up of 14 (6-36) months, six patients maintained a response (bortezomib/dexamethasone maintenance |
| DOI | 10.1111/bjh.16009 |