Hints for control of infection in unique extrahepatic vertebral alveolar echinococcosis

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TitreHints for control of infection in unique extrahepatic vertebral alveolar echinococcosis
Type de publicationJournal Article
Year of Publication2017
AuteursFaucher J-F, Descotes-Genon C, Hoen B, Godard J, Felix S, Aubry S, Blagosklonov O, Grenouillet F, Brientini M-P, Richou C, Bresson-Hadni S, Chirouze C
JournalINFECTION
Volume45
Pagination365-368
Date PublishedJUN
Type of ArticleArticle
ISSN0300-8126
Mots-clésAlveolar echinococcosis, cure, therapeutic drug monitoring, Vertebral
Résumé

The prognosis of vertebral alveolar echinococcosis (AE) is poor. We report on the unique outcome of a patient with preexisting liver cirrhosis, in whom a diagnosis of vertebral AE was established on vertebral histopathology (D4 corporectomy in 2010 for paraplegia). Therapeutic drug monitoring of albendazole (ABZ) showed that a low dosage was appropriate. The patient recovered and ABZ withdrawal was decided in 2014, with no relapse 18 months later. In this patient, infection was purely or mainly localized in the dorsal spine, and this may have been favored by liver cirrhosis. A longer follow-up is, however, needed to confirm cure.

DOI10.1007/s15010-016-0974-z