Transaortic transcatheter aortic valve implantation as a first-line choice or as a last resort? An analysis based on the ROUTE registry

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TitreTransaortic transcatheter aortic valve implantation as a first-line choice or as a last resort? An analysis based on the ROUTE registry
Type de publicationJournal Article
Year of Publication2017
AuteursBonaros N, Petzina R, Cocchieri R, Jagielak D, Aiello M, Lapeze J, Laine M, Chocron S, Muir D, Eichinger W, Thielmann M, Labrousse L, Bapat V, Rein KArne, Verhoye J-P, Gerosa G, Baumbach H, Kofler M, Bramlage P, Deutsch C, Thoenes M, Frank D, Romano M
JournalEUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
Volume51
Pagination919-926
Date PublishedMAY
Type of ArticleArticle; Proceedings Paper
ISSN1010-7940
Mots-clésSAPIEN, TAVI, transaortic, transapical, transcatheter aortic valve implantation, transfemoral
Résumé

{OBJECTIVES: Transaortic transcatheter aortic valve implantation (TAo-TAVI) is a recently developed alternative to transapical (TA) or transfemoral (TF) TAVI. We aimed to analyse the effectiveness and safety of TAo-TAVI as a first line approach and to compare it to patients receiving TAo-TAVI as a last resort, which is current practice. METHODS: ROUTE is a prospective, multicentre registry to assess the clinical outcomes of TAo-TAVI. Patients without contraindications for TA-and TF-TAVI (TAo-first) were compared to patients with contraindications for both of these access routes (TAo-last). Outcome analysis was based on VARC II defined clinical end-points. RESULTS: Three hundred and one patients were included, of which 224 patients met TAo-first and 77 TAo-last criteria. The valve was delivered and catheter retrieved successfully in all patients. In the TAo-first group, rates of conversion to open surgery and requirement for a second valve were low and not different compared to TAo-last patients (1% vs. 3%
DOI10.1093/ejcts/ezw406