PCSK9 levels do not predict severity and recurrence of cardiovascular events in patients with acute myocardial infarction
| Affiliation auteurs | !!!! Error affiliation !!!! |
| Titre | PCSK9 levels do not predict severity and recurrence of cardiovascular events in patients with acute myocardial infarction |
| Type de publication | Journal Article |
| Year of Publication | 2021 |
| Auteurs | Zeller M, Lambert G, Farnier M, Maza M, Nativel B, Rochette L, Vergely C, Cottin Y |
| Journal | NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES |
| Volume | 31 |
| Pagination | 880-885 |
| Date Published | MAR 10 |
| Type of Article | Article |
| ISSN | 0939-4753 |
| Mots-clés | acute myocardial infarction, Cohort studies, Hypercholesterolemia, PCSK9, prognosis |
| Résumé | {Background and aims: It remains unclear whether serum PCSK9 levels can predict the severity of the disease and the risk of future events in patients with coronary artery disease (CAD). We aimed to evaluate the association between PCSK9 levels, metabolic parameters, severity of CAD on coronary angiography (SYNTAX score), and the risk of in-hospital events and at one-year follow-up. Methods and results: From September 2015 to December 2016, serum PCSK9 levels were measured on admission in patients not previously receiving statin therapy, and admitted for an acute myocardial infarction (MI), in an intensive care unit from a university hospital. In a total of 648 patients (mean age: 66 years, 67% male), median PCSK9 was 263 ng/ml, higher for females compared with males (270 vs 256 ng/ml |
| DOI | 10.1016/j.numecd.2020.11.010 |