Does prenatal diagnosis modify neonatal management and early outcome of children with esophageal atresia type III?
| Affiliation auteurs | !!!! Error affiliation !!!! |
| Titre | Does prenatal diagnosis modify neonatal management and early outcome of children with esophageal atresia type III? |
| Type de publication | Journal Article |
| Year of Publication | 2015 |
| Auteurs | Garabedian C., Sfeir R., Langlois C., Bonnard A., Khen-Dunlop N., Gelas T., Michaud L., Auber F., Piolat C., Lemelle J.-L, Fouquet V., Habonima E., Becmeur F., Polimerol M.-L, Breton A., Petit T., Podevin G., Lavrand F., Allal H., Lopez M., Elbaz F., Merrot T., Michel J.-L, Buisson P., Sapin E., Delagausie P., Pelatan C., Gaudin J., Weil D., de Vries P., Jaby O., Lardy H., Aubert D., Borderon C., Fourcade L., Geiss S., Breaud J., Pouzac M., Echaieb A., Laplace C., Gottrand F., Houfflin-Debarge V. |
| Journal | JOURNAL DE GYNECOLOGIE OBSTETRIQUE ET BIOLOGIE DE LA REPRODUCTION |
| Volume | 44 |
| Pagination | 848-854 |
| Date Published | NOV |
| Type of Article | Article |
| ISSN | 0368-2315 |
| Mots-clés | Associated malformations, Esophageal atresia, Post-natal diagnosis, Prenatal diagnosis, VACTERL |
| Résumé | {Objective. Evaluate neonatal management and outcome of neonates with either a prenatal or a post-natal diagnosis of EA type III. Study design. Population-based study using data from the French National Register for EA from 2008 to 2010. We compared children with prenatal versus post-natal diagnosis in regards to prenatal, maternal and neonatal characteristics. We define a composite variable of morbidity (anastomotic esophageal leaks, recurrent fistula, stenosis) and mortality at 1 year. Results. Four hundred and eight live births with EA type III were recorded with a prenatal diagnosis rate of 18.1%. Transfer after birth was lower in prenatal subset (32.4% versus 81.5%, P < 0.001). Delay between birth and first intervention was not significantly different. Defect size (2 cm vs 1.4 cm, P < 0.001), gastrostomy (21.6% versus 8.7%, P < 0001) and length in neonatal unit care were higher in prenatal subset (47.9 days versus 33.6 days, P < 0.001). The composite variables were higher in prenatal diagnosis subset (38.7% vs 26.1% |
| DOI | 10.1016/j.jgyn.2014.12.004 |