Fast-Growing Alveolar Echinococcosis Following Lung Transplantation
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Titre | Fast-Growing Alveolar Echinococcosis Following Lung Transplantation |
Type de publication | Journal Article |
Year of Publication | 2020 |
Auteurs | Dupont C, Grenouillet F, Mabrut J-Y, Gay F, Persat F, Wallon M, Mornex J-F, Philit F, Dupont D |
Journal | PATHOGENS |
Volume | 9 |
Pagination | 756 |
Date Published | SEP |
Type of Article | Article |
Mots-clés | Echinococcus multilocularis, immunosuppression, Liver, lung transplantation, parasite |
Résumé | Alveolar echinococcosis is a rare but life-threatening infection caused by the parasiteEchinococcus multilocularis. Its natural history is characterized by a slow parasitic growth over several years. Increased incidence and shorter development delay have been reported in immune-compromised patients. We report the reactivation of aborted lesions within 12 months of lung transplantation leading to a fast-growing aggressive hepatic lesion. Timely identification of alveolar echninococcosis allowed prompt albendazole treatment and radical surgery leading to a favorable outcome 42 months after transplantation. However, close clinical, serological and radiological monitoring is required to rule out relapses in the long term. The pre-existence of aborted self-limited lesions of alveolar echinococcosis and the possibility for their atypical rapid growth in patients undergoing profound immunosuppression should be known by healthcare providers, even if working in non-endemic areas. |
DOI | 10.3390/pathogens9090756 |