Long-Term Evaluation of Gadolinium Retention in Rat Brain After Single Injection of a Clinically Relevant Dose of Gadolinium-Based Contrast Agents

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TitreLong-Term Evaluation of Gadolinium Retention in Rat Brain After Single Injection of a Clinically Relevant Dose of Gadolinium-Based Contrast Agents
Type de publicationJournal Article
Year of Publication2020
AuteursStrzeminska I, Factor C, Robert P, Grindel A-L, Comby P-O, Szpunar J, Corot C, Lobinski R
JournalINVESTIGATIVE RADIOLOGY
Volume55
Pagination138-143
Date PublishedMAR
Type of ArticleArticle
ISSN0020-9996
Mots-cléscerebellum, gadobenate, gadodiamide, gadolinium retention, gadolinium species, gadolinium-based contrast agent, gadoterate
Résumé

{Purpose The aim of this study was to investigate the presence and chemical forms of residual gadolinium (Gd) in rat brain after a single dose of Gd-based contrast agent. Methods Four groups of healthy rats (2 sacrifice time-points

DOI10.1097/RLI.0000000000000623