Multimodal Percutaneous Thermal Ablation of Small Hepatocellular Carcinoma: Predictive Factors of Recurrence and Survival in Western Patients

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TitreMultimodal Percutaneous Thermal Ablation of Small Hepatocellular Carcinoma: Predictive Factors of Recurrence and Survival in Western Patients
Type de publicationJournal Article
Year of Publication2020
AuteursHermida M, Cassinotto C, Piron L, Aho-Glele S, Guillot C, Schembri V, Allimant C, Jaber S, Pageaux G-P, Assenat E, Guiu B
JournalCANCERS
Volume12
Pagination313
Date PublishedFEB
Type of ArticleArticle
Mots-cléshepatocellular carcinoma, Liver, Microwave ablation, percutaneous thermal ablation, radiofrequency ablation, Recurrence, survival
Résumé

{Background: To identify the predictive factors of recurrence and survival in an unselected population of Western patients who underwent multimodal percutaneous thermal ablation (PTA) for small Hepatocellular Carcinomas (HCCs). Methods: January 2015-June 2019: data on multimodal PTA for <3 cm HCC were extracted from a prospective database. Local tumor progression (LTP), intrahepatic distant recurrence (IDR), time-to-LTP, time-to-IDR, recurrence-free (RFS) and overall (OS) survival were evaluated. Results: 238 patients underwent 317 PTA sessions to treat 412 HCCs. During follow-up (median: 27.1 months), 47.1% patients had IDR and 18.5% died. LTP occurred after 13.3% of PTA. Tumor size (OR = 1.108, p < 0.001; hazard ratio (HR) = 1.075
DOI10.3390/cancers12020313