Influence of alternative donor type on early survival after hematopoietic stem cell transplantation for acute myeloid leukemia lacking a sibling donor

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TitreInfluence of alternative donor type on early survival after hematopoietic stem cell transplantation for acute myeloid leukemia lacking a sibling donor
Type de publicationJournal Article
Year of Publication2020
AuteursDeteix C, Mesnil F, Furst S, Milpied N, Yakoub-Agha I, Fegueux N, de Latour RPeffault, Mohty M, Chevallier P, Wallet HLabussiere, Huynh A, Larosa F, Bourhis J-H, Cahn J-Y, Chantepie S, Bay J-O, Audat F, Foote A, Faucher C, Marry E, Garban F, Moelle SFrancophon, Th
JournalBONE MARROW TRANSPLANTATION
Volume55
Pagination749-757
Date PublishedAPR
Type of ArticleArticle
ISSN0268-3369
Résumé

{Allogeneic hematopoietic stem cell transplantation is the only potentially curative therapy for acute myeloid leukemia. In the absence of an HLA-matched related or unrelated donor (MRD or MUD), the best alternative donor source remains controversial. Umbilical cord blood and haploidentical donors offer a shorter delay from indication to transplantation. This retrospective multicentre study of a French registry compares overall survival in the 18 months following registration in the absence of a MRD between four types of donors. Between 2012 and 2016, 1302 patients were transplanted using MUD (control
DOI10.1038/s41409-019-0722-y