Factors influencing patient's perception of long-term treatment with low-molecular-weight heparins for cancer-associated thrombosis: an updated analysis of TROPIQUE, a prospective observational study

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TitreFactors influencing patient's perception of long-term treatment with low-molecular-weight heparins for cancer-associated thrombosis: an updated analysis of TROPIQUE, a prospective observational study
Type de publicationJournal Article
Year of Publication2020
AuteursDebourdeau P., Arvers P., Hij A., Bennani H., Desauw C., Falvo N., Ghiringhelli F., Hamade A., Vedrine L., Farge D.
JournalSUPPORTIVE CARE IN CANCER
Volume28
Pagination287-293
Date PublishedJAN
Type of ArticleArticle
ISSN0941-4355
Mots-clésAcceptability, Cancer, Experience, LMWH, Quality of life, Venous thromboembolism
Résumé

{Purpose Our objective was to compare patient's expectations to their experience and to identify factors predictive of patient's perception of long-term LMWH for the treatment of cancer-associated thrombosis (CAT). Methods Results from the validated Perception Anticoagulant Treatment Questionnaires (PACTQ) completed before inclusion (PACTQ1 for expectations) and at the end (PACTQ2 for convenience and satisfaction) of the 6-month TROPIQUE study were studied with principal component analysis. Possible predictive factors of improved perception of LMWH treatment were analyzed with the Kruskall-Wallis test. Results Among 409 included patients treated with LMWH, 269 PACT-Q1 and 139 PACT-Q2 were evaluable for treatment perception. Patients had high expectations (A1-A7 score of 26.7 +/- 3.5
DOI10.1007/s00520-019-04815-z