Evaluation of the Immunochromatographic NG-Test Carba 5 for Rapid Identification of Carbapenemase in Nonfermenters

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TitreEvaluation of the Immunochromatographic NG-Test Carba 5 for Rapid Identification of Carbapenemase in Nonfermenters
Type de publicationJournal Article
Year of Publication2019
AuteursPotron A, Fournier D, Emeraud C, Triponney P, Plesiat P, Naas T, Dortet L
JournalANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume63
Paginatione00968-19
Date PublishedSEP
Type of ArticleArticle
ISSN0066-4804
Mots-clésAcinetobacter, carbapenemases, IMP, KPC, NDM, Pseudomonas aeruginosa, rapid diagnostic, VIM
Résumé

The immunochromatographic assay NG-Test Carba 5 (NG-Biotech) was evaluated with a collection of 107 carbapenemase-producing nonfermenters (CP-NF) (55 Pseudomonas spp., 51 Acinetobacter spp., and 1 Achromobacter xylosoxidans isolate) and 61 carbapenemase-negative isolates. All KPC, VIM, and NDM carbapenemase producers tested were accurately detected. Of the 16 IMP variants tested, 6 (37.5%) variants were not detected. Considering the epidemiology of CP-NFs in France, the NG-Test Carba 5 would detect 89.4% of CP Pseudomonas spp. but only 12.9% of CP Acinetobacter spp.

DOI10.1128/AAC.00968-19