Alternative donors for allogeneic hematopoietic stem cell transplantation in poor-risk AML in CR1

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TitreAlternative donors for allogeneic hematopoietic stem cell transplantation in poor-risk AML in CR1
Type de publicationJournal Article
Year of Publication2017
AuteursVersluis J, Labopin M, Ruggeri A, Socie G, Wu D, Volin L, Blaise D, Milpied N, Craddock C, Yakoub-Agha I, Maertens J, Ljungman P, Huynh A, Michallet M, Deconinck E, Chevallier P, Passweg J, Ciceri F, Mohty M, Cornelissen JJ, Nagler A, Europ ALeukemia W
JournalBLOOD ADVANCES
Volume1
Pagination477-485
Date PublishedFEB 28
Type of ArticleArticle
ISSN2473-9529
Résumé

{Allogeneic hematopoietic stem cell transplantation (alloHSCT) remains the treatment of choice to consolidate remission in patients with poor-risk acute myeloid leukemia (AML). With increasing alternative donors available, the preferred donor or stem cell source is debated. We set out to study outcome in recipients of alloHSCT with poor-risk AML in first complete remission (CR1) by donor type. A total of 6545 adult patients with poor-risk AML in CR1 receiving an alloHSCT using matched related donor (MRD
DOI10.1182/bloodadvances.2016002386