Molecular epidemiology of OXA-48-producing Klebsiella pneumoniae in France
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Titre | Molecular epidemiology of OXA-48-producing Klebsiella pneumoniae in France |
Type de publication | Journal Article |
Year of Publication | 2014 |
Auteurs | Liapis E., Pantel A., Robert J., Nicolas-Chanoine M.-H, Cavalie L., van der Mee-Marquet N., de Champs C., Aissa N., Eloy C., Blanc V., Guyeux C., Hocquet D., Lavigne J.-P, Bertrand X., ONERBA |
Journal | CLINICAL MICROBIOLOGY AND INFECTION |
Volume | 20 |
Pagination | O1121-O1123 |
Date Published | DEC |
Type of Article | Article |
ISSN | 1198-743X |
Mots-clés | Multidrug resistance, multilocus sequence typing, phylogenetic analysis |
Résumé | We characterized 53 OXA-48-producing Klebsiella pneumoniae (OXA-48-Kp) isolated between 2011 and 2013 in 21 French hospitals. All the isolates were genotyped using MLST and PFGE and the population structure of the species was determined by a nucleotide-based analysis of the entire K.pneumoniae MLST database. Most of the OXA-48-Kp isolates also produced CTX-M-15 and remained susceptible to imipenem and meropenem. The isolates were distributed into 20 STs, of which five were dominant (ST15, ST101, ST147, ST395 and ST405). All the OXA-48-Kp clustered in the major clade of K.pneumoniae KpI. |
DOI | 10.1111/1469-0691.12727 |