Molecular epidemiology of OXA-48-producing Klebsiella pneumoniae in France

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TitreMolecular epidemiology of OXA-48-producing Klebsiella pneumoniae in France
Type de publicationJournal Article
Year of Publication2014
AuteursLiapis E., Pantel A., Robert J., Nicolas-Chanoine M.-H, Cavalie L., van der Mee-Marquet N., de Champs C., Aissa N., Eloy C., Blanc V., Guyeux C., Hocquet D., Lavigne J.-P, Bertrand X., ONERBA
JournalCLINICAL MICROBIOLOGY AND INFECTION
Volume20
PaginationO1121-O1123
Date PublishedDEC
Type of ArticleArticle
ISSN1198-743X
Mots-clésMultidrug resistance, multilocus sequence typing, phylogenetic analysis
Résumé

We characterized 53 OXA-48-producing Klebsiella pneumoniae (OXA-48-Kp) isolated between 2011 and 2013 in 21 French hospitals. All the isolates were genotyped using MLST and PFGE and the population structure of the species was determined by a nucleotide-based analysis of the entire K.pneumoniae MLST database. Most of the OXA-48-Kp isolates also produced CTX-M-15 and remained susceptible to imipenem and meropenem. The isolates were distributed into 20 STs, of which five were dominant (ST15, ST101, ST147, ST395 and ST405). All the OXA-48-Kp clustered in the major clade of K.pneumoniae KpI.

DOI10.1111/1469-0691.12727