B Cells and Antibodies in Transplantation
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Titre | B Cells and Antibodies in Transplantation |
Type de publication | Journal Article |
Year of Publication | 2016 |
Auteurs | Koenig A, Mariat C, Mousson C, Wood KJ, Rifle G, Thaunat O |
Journal | TRANSPLANTATION |
Volume | 100 |
Pagination | 1460-1464 |
Date Published | JUL |
Type of Article | Review |
ISSN | 0041-1337 |
Résumé | Overlooked for decades, the humoral alloimmune response is increasingly recognized as a leading cause of graft loss after transplantation. However, improvement in the diagnosis of antibody-mediated rejection has not yet translated into better outcomes for transplanted patients. After an update on B cell physiology and antibody generation, the 2015 Beaune Seminar in Transplant Research challenged the conventional view of antibody-mediated rejection pathophysiology and discussed the latest promising therapeutic approaches. |
DOI | 10.1097/TP.0000000000001069 |