Hidradenitis suppurativa (HS): An unrecognized paradoxical effect of biologic agents (BA) used in chronic inflammatory diseases

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TitreHidradenitis suppurativa (HS): An unrecognized paradoxical effect of biologic agents (BA) used in chronic inflammatory diseases
Type de publicationJournal Article
Year of Publication2016
AuteursFaivre C, Villani APatrice, Aubin F, Lipsker D, Bottaro M, Cohen J-D, Durupt F, Jeudy G, Sbidian E, Toussirot E, Badot V, Barbarot S, Debarbieux S, Delaporte E, Goegebeur G, Morel J, Nassif A, Duru G, Jullien D, Club FSoc Dermat
JournalJOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Volume74
Pagination1153-1159
Date PublishedJUN
Type of ArticleArticle
ISSN0190-9622
Mots-clésbiologic agents, HIDRADENITIS SUPPURATIVA, paradoxical reactions, tumor necrosis factor-alfa inhibitors
Résumé

{Background: Paradoxical hidradenitis suppurativa (HS) induced by biologic agents (BA) is scarcely reported. Objective: We sought to describe the clinical characteristics and outcome of patients developing paradoxical HS under BA. Methods: This was a multicenter nationwide retrospective study asking physicians to report all cases of HS, confirmed by a dermatologist, occurring during treatment of an inflammatory disease by a BA. Results: We included 25 patients (15 inflammatory rheumatism, 9 Crohn's disease, 1 psoriasis) treated by 5 BA (adalimumab = 12
DOI10.1016/j.jaad.2016.01.018