Transcranial direct current stimulation for acute major depressive episodes: meta-analysis of individual patient data
Affiliation auteurs | !!!! Error affiliation !!!! |
Titre | Transcranial direct current stimulation for acute major depressive episodes: meta-analysis of individual patient data |
Type de publication | Journal Article |
Year of Publication | 2016 |
Auteurs | Brunoni AR, Moffa AH, Fregni F, Palm U, Padberg F, Blumberger DM, Daskalakis ZJ, Bennabi D, Haffen E, Alonzo A, Loo CK |
Journal | BRITISH JOURNAL OF PSYCHIATRY |
Volume | 208 |
Pagination | 522+ |
Date Published | JUN |
Type of Article | Review |
ISSN | 0007-1250 |
Résumé | {Background Transcranial direct current stimulation (tDCS) is a non-pharmacological intervention for depression. It has mixed results, possibly caused by study heterogeneity. Aims To assess tDCS efficacy and to explore individual response predictors. Method Systematic review and individual patient data meta-analysis. Results Data were gathered from six randomised sham-controlled trials, enrolling 289 patients. Active tDCS was significantly superior to sham for response (34% v. 19% respectively, odds ratio (OR) = 2.44, 95% CI 1.38-4.32, number needed to treat (NNT) = 7), remission (23.1% v. 12.7% respectively |
DOI | 10.1192/bjp.bp.115.164715 |