Trichodysplasia spinulosa: a polyomavirus infection specifically targeting follicular keratinocytes in immunocompromised patients

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TitreTrichodysplasia spinulosa: a polyomavirus infection specifically targeting follicular keratinocytes in immunocompromised patients
Type de publicationJournal Article
Year of Publication2016
AuteursRouanet J., Aubin F., Gaboriaud P., Berthon P., Feltkamp M.C, Bessenay L., Touze A., Nicol J.TJ, Franck F., d'Incan M.
JournalBRITISH JOURNAL OF DERMATOLOGY
Volume174
Pagination629-632
Date PublishedMAR
Type of ArticleArticle
ISSN0007-0963
Résumé

Trichodysplasia spinulosa (TS) is a rare skin disease, caused by a specific polyomavirus, occurring in immunocompromised patients. The pathophysiological mechanisms of TS are not yet fully understood. By using polymerase chain reaction and skin biopsy immunostaining we report evidence, in a paediatric case, of follicular keratinocytes being the primary target of trichodysplasia spinulosa-associated polyomavirus.

DOI10.1111/bjd.14346