Fatal case of acute gastroenteritis with multiple viral coinfections

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TitreFatal case of acute gastroenteritis with multiple viral coinfections
Type de publicationJournal Article
Year of Publication2016
AuteursLupo J, Morel-Baccard C, Michard-Lenoir A-P, Germi R, Pothier P, Ambert-Balay K, Morand P
JournalJOURNAL OF CLINICAL VIROLOGY
Volume74
Pagination54-56
Date PublishedJAN
Type of ArticleArticle
ISSN1386-6532
Mots-clésAcute gastroenteritis, Autism spectrum disorder, coinfection, Cycle threshold value, enteric viruses, Viral load
Résumé

We report a fatal case of acute gastroenteritis in a child with autism spectrum disorder. Multiple viral coinfections were detected by PCR in the patient's stool and digestive biopsy specimens. As viral detection is not necessarily associated with symptomatic disease, a semi-quantitative approach using cycle treshold values was proposed for the clinical interpretation of PCR. We discuss whether concomitant viral infections could be a risk factor for severe outcome in gastroenteritis cases. Individual risk factors are also addressed. (C) 2015 Elsevier B.V. All rights reserved.

DOI10.1016/j.jcv.2015.11.026