Tubular and mucinous breast cancer: results of a cohort of 917 patients

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TitreTubular and mucinous breast cancer: results of a cohort of 917 patients
Type de publicationJournal Article
Year of Publication2019
AuteursRoux P, Knight S, Cohen M, Classe JMarc, Mazouni C, Chauvet M-P, Reyal F, Colombo P-E, Jouve E, Chopin N, Darai E, Coutant C, Lambaudie E, Houvenaeghel G
JournalTUMORI JOURNAL
Volume105
Pagination55-62
Date PublishedFEB
Type of ArticleArticle
ISSN0300-8916
Mots-clésaxillary lymph node involvement, Breast cancer, mucinous carcinoma, survival, tubular carcinoma
Résumé

{Objectives: To analyze axillary lymph node involvement (ALNI) rate and survival for mucinous (MC) and tubular (TC) breast carcinomas considered being of very good prognosis and for which an axillary surgical exploration could be questioned. Methods: Our multicentric cohort consisted of 21,135 patients with clinically node-negative invasive breast cancer, without neoadjuvant therapy, between 1999 and 2013 in 10 French centers. ALNI rate and survival were analyzed according to patient and tumor characteristics. Results: Our cohort consisted of 672 TC and 245 MC. Patients were older and tumor size greater for MC and pathologic factors were more pejorative. The rate of mastectomies and adjuvant chemotherapy was higher in the MC group. Axillary lymph node status was determined by SLNB alone in 71.2% of patients. ALNI rates were 17.9% and 18% for TC and MC, respectively. ALNI rate was lesser for MC (OR 0.503

DOI10.1177/0300891618811282