Cell lines and immune classification of glioblastoma define patient's prognosis

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TitreCell lines and immune classification of glioblastoma define patient's prognosis
Type de publicationJournal Article
Year of Publication2019
AuteursKlopfenstein Q, Truntzer C, Vincent J, Ghiringhelli F
JournalBRITISH JOURNAL OF CANCER
Volume120
Pagination806-814
Date PublishedAPR 16
Type of ArticleArticle
ISSN0007-0920
Résumé

{BACKGROUND: Prognostic markers for glioblastoma are lacking. Both intrinsic tumour characteristics and microenvironment could influence cancer prognostic. The aim of our study was to generate a pure glioblastoma cell lines and immune classification in order to decipher the respective role of glioblastoma cell and microenvironment on prognosis. METHODS: We worked on two large cohorts of patients suffering from glioblastoma (TCGA

DOI10.1038/s41416-019-0404-y