Breast-conserving treatment for ductal carcinoma in situ: Impact of boost and tamoxifen on local recurrences

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TitreBreast-conserving treatment for ductal carcinoma in situ: Impact of boost and tamoxifen on local recurrences
Type de publicationJournal Article
Year of Publication2016
AuteursCutuli B., Wiezzane N., Palumbo I., Barbieri P., Guenzi M., Huscher A., Borghesi S., Delva C., Iannone T., Vianello E., Rosetto M.-E, Aristei C.
JournalCANCER RADIOTHERAPIE
Volume20
Pagination292-298
Date PublishedJUN
Type of ArticleArticle
ISSN1278-3218
Mots-clésBoost, Breast-conserving therapy, DCIS, local recurrence, Nuclear grade, Tamoxifen, treatment
Résumé

{Purpose. - Ductal carcinoma in situ represents 15 to 20% of all breast cancers. Breast-conserving surgery and whole breast irradiation was performed in about 60% of the cases. This study reports local recurrence rates in patients with ductal carcinoma in situ treated by breast-conserving surgery and whole breast irradiation with or without boost and/or tamoxifen and compares different therapeutic options in two European countries. Patients and methods. - From 1998 to 2007, 819 patients with pure ductal carcinoma in situ were collected, both in France (266) and Italy (553). Median age was 56. All underwent breast-conserving surgery and whole breast irradiation; 391 (48%) received a boost (55% in France and 45% in Italy

DOI10.1016/j.canrad.2016.04.004