Azole-Resistant Aspergillus fumigatus Isolate with the TR34/L98H Mutation in Both a Fungicide-Sprayed Field and the Lung of a Hematopoietic Stem Cell Transplant Recipient with Invasive Aspergillosis
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Titre | Azole-Resistant Aspergillus fumigatus Isolate with the TR34/L98H Mutation in Both a Fungicide-Sprayed Field and the Lung of a Hematopoietic Stem Cell Transplant Recipient with Invasive Aspergillosis |
Type de publication | Journal Article |
Year of Publication | 2014 |
Auteurs | Rocchi S, Daguindau E, Grenouillet F, Deconinck E, Bellanger A-P, Garcia-Hermoso D, Bretagne S, Reboux G, Millon L |
Journal | JOURNAL OF CLINICAL MICROBIOLOGY |
Volume | 52 |
Pagination | 1724-1726 |
Date Published | MAY |
Type of Article | Article |
ISSN | 0095-1137 |
Résumé | A French farmer developed invasive aspergillosis with azole-resistant Aspergillus fumigatus with the TR34/L98H mutation following a hematopoietic stem cell transplantation. He had worked in fungicide-sprayed fields where a non-genetically related A. fumigatus TR34/L98H isolate was collected. If azole resistance detection increases, voriconazole as first-line therapy might be questioned in agricultural areas. |
DOI | 10.1128/JCM.03182-13 |