Triterpene saponins from the roots of Bupleurum spinosum Gouan

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TitreTriterpene saponins from the roots of Bupleurum spinosum Gouan
Type de publicationJournal Article
Year of Publication2020
AuteursDahmoune A, Smati D, Mitaine-Offer A-C, Miyamoto T, Tanaka C, Paululat T, Lacaille-Dubois M-A
JournalPHYTOCHEMISTRY LETTERS
Volume39
Pagination157-161
Date PublishedOCT
Type of ArticleArticle
ISSN1874-3900
Mots-clésApiaceae, Bupleurum spinosum, NMR spectroscopy, Triterpene saponins
Résumé

Three previously undescribed triterpene saponins, and four known ones, were isolated from the EtOH/H2O extract of the roots of Bupleurum spinosum. Their structures were characterized using spectroscopic techniques including 1D and 2D NMR (H-1, C-13, COSY, TOCSY, ROESY, HSQC, and HMBC) experiments and mass spectrometry as 3-O-beta-D-glucopyranosyl-(1 -> 6)-[beta-D-glucopyranosyl-(1 -> 2)]-[alpha-L-rhamnopyranosyl-(1 -> 4)]-beta-D-glucopyranosyl-3 beta,16 beta,23,28-tetrahydroxyolean-12-ene, 3-O-beta-D-glucopyranosyl-(1 -> 6)-[beta-D-glucopyranosyl-(1 -> 2)]-[alpha-L-rhamnopyranosyl-(1 -> 4)]-beta-D-glucopyranosyl-3 beta,16 beta,28-trihydroxy-23-oxoolean-12-ene, 3-O-beta-D-glucopyranosyl-(1 -> 6)-[alpha-L-rhamnopyranosyl(1 -> 4)]-beta-D-glucopyranosyl-3 beta,16 beta,28-trihydroxyolean-12-ene-23-oic-acid. The chemotaxonomic significance is underlined.

DOI10.1016/j.phytol.2020.08.007