Role of fluorine 18 fluorodeoxyglucose positron emission tomography/computed tomography in gastrointestinal cancers

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TitreRole of fluorine 18 fluorodeoxyglucose positron emission tomography/computed tomography in gastrointestinal cancers
Type de publicationJournal Article
Year of Publication2015
AuteursGauthe M, Richard-Molard M, Cacheux W, Michel P, Jouve J-L, Mitry E, Alberini J-L, Lievre A, Di FFrancophon
JournalDIGESTIVE AND LIVER DISEASE
Volume47
Pagination443-454
Date PublishedJUN
Type of ArticleReview
ISSN1590-8658
Mots-clésAnal canal cancer, Colorectal cancer, FDG-PET/CT, Oesophageal cancer, pancreatic cancer
Résumé

Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) has become a routine imaging modality for many malignancies and its use is currently increasing. In the present review article, we will summarize the evidence for FDG-PET/CT use in digestive cancers (excluding neuroendocrine tumours), and review the existing recommendations. While PET/CT is nowadays considered to be an important tool in the initial workup of oesophageal and anal cancers, new data are emerging regarding its use in assessing therapeutic efficacy, radiotherapy treatment planning, and detection of recurrence in case of isolated tumour marker elevation. Moreover, PET/CT may help decision making by detecting distant metastatic sites especially in potentially resectable metastatic colorectal cancer and, to a lesser extent, in localized gastric and pancreatic cancers. Finally, incidental focal colonic FDG uptakes require exploration by colonoscopy, as they are often associated with premalignant or malignant lesions. (C) 2015 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

DOI10.1016/j.dld.2015.02.005