Occupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study
Affiliation auteurs | !!!! Error affiliation !!!! |
Titre | Occupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study |
Type de publication | Journal Article |
Year of Publication | 2015 |
Auteurs | Costas L., Infante-Rivard C., Zock J-P, Van Tongeren M., Boffetta P., Cusson A., Robles C., Casabonne D., Benavente Y., Becker N., Brennan P., Foretova L., Maynadie M., Staines A., Nieters A., Cocco P., de Sanjose S. |
Journal | BRITISH JOURNAL OF CANCER |
Volume | 112 |
Pagination | 1251-1256 |
Date Published | MAR 31 |
Type of Article | Article |
ISSN | 0007-0920 |
Mots-clés | Alkylphenols, chemicals, endocrine disruptors, leukaemia, lymphoma, pesticides, solvents |
Résumé | Background: Incidence rates of lymphoma are usually higher in men than in women, and oestrogens may protect against lymphoma. Methods: We evaluated occupational exposure to endocrine disrupting chemicals (EDCs) among 2457 controls and 2178 incident lymphoma cases and subtypes from the European Epilymph study. Results: Over 30 years of exposure to EDCs compared to no exposure was associated with a 24% increased risk of mature B-cell neoplasms (P-trend = 0.02). Associations were observed among men, but not women. Conclusions: Prolonged occupational exposure to endocrine disruptors seems to be moderately associated with some lymphoma subtypes. |
DOI | 10.1038/bjc.2015.83 |