IAPs and cell migration

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TitreIAPs and cell migration
Type de publicationJournal Article
Year of Publication2015
AuteursDubrez L, Rajalingam K
JournalSEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Volume39
Pagination124-131
Date PublishedMAR
Type of ArticleReview
ISSN1084-9521
Mots-clésIAPS, Invasion, Migration, RhoGTPases, Signaling, Ubiquitination
Résumé

Inhibitors of apoptosis (IAPs) constitute a family of cell signaling regulators controlling several fundamental biological processes such as innate immunity, inflammation, cell death, cell proliferation, and cell differentiation. Increasing evidence from in vivo and in vitro studies indicate a function for IAPs in the modulation of invasive and migratory properties of cells. Here, we present and discuss the mechanisms whereby IAPs can control cell migration. (C) 2015 Elsevier Ltd. All rights reserved.

DOI10.1016/j.semcdb.2015.02.015