Associations of long-term physical activity trajectories with coronary artery calcium progression and cardiovascular disease events: results from the CARDIA study

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TitreAssociations of long-term physical activity trajectories with coronary artery calcium progression and cardiovascular disease events: results from the CARDIA study
Type de publicationJournal Article
Year of PublicationSubmitted
AuteursGao J-W, Hao Q-Y, Lu L-Y, Han J-J, Huang F-F, Vuitton DA, Wang J-F, Zhang S-L, Liu P-M
JournalBRITISH JOURNAL OF SPORTS MEDICINE
Type of ArticleArticle; Early Access
ISSN0306-3674
Mots-cléscardiovascular diseases, Physical activity
Résumé

{Objective The study aimed to assess the associations of physical activity (PA) trajectories across a 25-year span with coronary artery calcium (CAC) progression, and subsequent risk of cardiovascular disease (CVD) events. Methods We included 2497 participants from the Coronary Artery Disease Risk Development in Young Adults study who had computed tomography-assessment of CAC at baseline (year 15: 2000-2001) and follow-up (year 20 or 25) and at least three measures of PA from year 0 to year 25. Long-term PA trajectories were determined by latent class modelling using a validated questionnaire. Results Among the included participants, 1120 (44.9%) were men, 1418 (56.8%) were white, and the mean (SD) age was 40.4 (3.6) years. We identified three distinct PA trajectories based on PA average levels and change patterns: low (below PA guidelines

DOI10.1136/bjsports-2021-105092