Five Functional Aspects of the Epidermal Barrier

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TitreFive Functional Aspects of the Epidermal Barrier
Type de publicationJournal Article
Year of Publication2021
AuteursLefevre-Utile A, Braun C, Haftek M, Aubin F
JournalINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume22
Pagination11676
Date PublishedNOV
Type of ArticleReview
Mots-clésceramides, desmosomes, epidermis, immunity, keratinization, microbiome, sensory nerves, skin barrier, stratum corneum, Tight junctions
Résumé

The epidermis is a living, multilayered barrier with five functional levels, including a physical, a chemical, a microbial, a neuronal, and an immune level. Altogether, this complex organ contributes to protect the host from external aggression and to preserve its integrity. In this review, we focused on the different functional aspects.

DOI10.3390/ijms222111676