Five Functional Aspects of the Epidermal Barrier
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Titre | Five Functional Aspects of the Epidermal Barrier |
Type de publication | Journal Article |
Year of Publication | 2021 |
Auteurs | Lefevre-Utile A, Braun C, Haftek M, Aubin F |
Journal | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
Volume | 22 |
Pagination | 11676 |
Date Published | NOV |
Type of Article | Review |
Mots-clés | ceramides, desmosomes, epidermis, immunity, keratinization, microbiome, sensory nerves, skin barrier, stratum corneum, Tight junctions |
Résumé | The epidermis is a living, multilayered barrier with five functional levels, including a physical, a chemical, a microbial, a neuronal, and an immune level. Altogether, this complex organ contributes to protect the host from external aggression and to preserve its integrity. In this review, we focused on the different functional aspects. |
DOI | 10.3390/ijms222111676 |