PF4 Immunoassays in Vaccine-Induced Thrombotic Thrombocytopenia
| Affiliation auteurs | !!!! Error affiliation !!!! |
| Titre | PF4 Immunoassays in Vaccine-Induced Thrombotic Thrombocytopenia |
| Type de publication | Journal Article |
| Year of Publication | 2021 |
| Auteurs | Vayne C, Rollin J, Gruel Y, Pouplard C, Galinat H, Huet O, Memier V, Geeraerts T, Marlu R, Pernod G, Mourey G, Fournel A, Cordonnier C, Susen S |
| Journal | NEW ENGLAND JOURNAL OF MEDICINE |
| Volume | 385 |
| Pagination | 376-378 |
| Date Published | JUL 22 |
| Type of Article | Letter |
| ISSN | 0028-4793 |
| Résumé | Laboratory Method to Detect VITT The rare vaccine-induced immune thrombotic thrombocytopenia that may follow adenovirus-based Covid-19 vaccination resembles heparin-induced thrombocytopenia, but rapid assays for anti-PF4 antibodies used to diagnose HIT may be negative in patients with VITT. The PF4-serotonin release assay appears to detect the IgG antibodies to PF4-PVS that mediate this condition. |
| DOI | 10.1056/NEJMc2106383 |