Efficient Stereoselective Synthesis of Boron L-Amino Acid Derivatives Using Wittig and Borylation Reactions
| Affiliation auteurs | !!!! Error affiliation !!!! |
| Titre | Efficient Stereoselective Synthesis of Boron L-Amino Acid Derivatives Using Wittig and Borylation Reactions |
| Type de publication | Journal Article |
| Year of Publication | 2015 |
| Auteurs | Audi H, Remond E, Eymin M-J, Tessier A, Malacea-Kabbara R, Juge S |
| Journal | PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS |
| Volume | 190 |
| Pagination | 953-954 |
| Date Published | JUN 3 |
| Type of Article | Article; Proceedings Paper |
| ISSN | 1042-6507 |
| Mots-clés | a-amino acids, boronates, iridium catalysis, trifluoroborates, Wittig reagent |
| Résumé | The stereoselective synthesis of a new classes of boronato- or trifluoroborato aminoacids and peptides was described using Wittig and C-H iridium borylation as key reactions. A trifluoroborato-thiophene aminoacid derivative showed an excellent stability in aqueous conditions, useful for further applications as radiotracers by F-18 labeling. |
| DOI | 10.1080/10426507.2014.979990 |