2018 Consensus of the French Society of Endocrinology: endocrine toxicities of cancer immunotherapies

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Titre2018 Consensus of the French Society of Endocrinology: endocrine toxicities of cancer immunotherapies
Type de publicationJournal Article
Year of Publication2019
AuteursCostinetti F, Borson-Chazot F, Aibarel F, Archambeaud F, Bertherat J, Bouillet B, Buffier P, Briet C, Cariou B, Caron P, Chabre O, Chanson P, Cortet C, Cao CDo, Drui D, Haissaguerre M, Hescot S, Illouz F, Kuhn E, Lahlou N, Merlen E, Raverot V, Smati S, Verges B, 2018 CSFE
JournalCORRESPONDANCES EN METABOLISMES HORMONES DIABETES ET NUTRITION
Volume23
Pagination31-36
Date PublishedMAR-APR
Type of ArticleArticle
ISSN2100-9619
Mots-clésadrenal insufficiency, diabetes, Hypophysitis, Immunotherapy, Thyroiditis
Résumé

Immunotherapy induced side effects: Are frequent, usually well-tolerated, and can lead to thyroid, pituitary, and less frequently adrenals and pancreas (fulminant diabetes) disease,. Do not contra-indicate immunotherapy, and rarely require high dose glucocorticoids; Need to be screened for, as there are acute manifestations, and replacement treatments can be given lifelong; Require a pre-immunotherapy evaluation; Require a careful follow-up at least during the first 6 months of immunotherapy.