Risk Factors of Early Mortality and Morbidity in Esophageal Atresia with Distal Tracheoesophageal Fistula: A Population-Based Cohort Study

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TitreRisk Factors of Early Mortality and Morbidity in Esophageal Atresia with Distal Tracheoesophageal Fistula: A Population-Based Cohort Study
Type de publicationJournal Article
Year of Publication2021
AuteursSfeir R, Rousseau V, Bonnard A, Gelas T, Aumar M, Panait N, Piolat C, Irtan S, Fouquet V, Lemandat A, De Napoli S, Habonimana E, Lamireau T, Lemelle JLouis, Baz FEl, Talon I, Polimerol MLaurence, Allal H, Buisson P, Petit T, Louis D, Lardy H, Schmitt F, Levard G, Scalabre A, Michel JLuc, Jaby O, Pelatan C, de Vries P, Borderon C, Fourcade L, Breaud J, Pouzac M, Tolg C, Chaussy Y, Ritz SJochault, Laplace C, Drumez E, Gottrand F
JournalJOURNAL OF PEDIATRICS
Volume234
Pagination99+
Date PublishedJUL
Type of ArticleArticle
ISSN0022-3476
Résumé

{Objective To identify the risk factors for early mortality and morbidity in a population with distal esophageal atresia (EA)-tracheoesophageal fistula. Study design Cohort study from a national register. Main outcomes and measures included early mortality, hospital length of stay (LoS), need for nutritional support at 1 year of age as a proxy measure of morbidity, and complications during the first year of life. Results In total, 1008 patients with a lower esophageal fistula were included from January 1, 2008, to December 31, 2014. The survival rate at 3 months was 94.9%. The cumulative hospital LoS was 31.0 (17.0-64.0) days. Multivariate analysis showed that intrahospital mortality at 3 months was associated with low birth weight (OR 0.52, 95% CI [0.38-0.72], P <.001), associated cardiac abnormalities (OR 6.09 [1.96-18.89]
DOI10.1016/j.jpeds.2021.02.064