Loss of X chromosome predicts favorable prognosis in female patients with t(8;21) acute myeloid leukemia
| Affiliation auteurs | !!!! Error affiliation !!!! |
| Titre | Loss of X chromosome predicts favorable prognosis in female patients with t(8;21) acute myeloid leukemia |
| Type de publication | Journal Article |
| Year of Publication | 2020 |
| Auteurs | Chen G, Zhou W, Gong D, Li Y, Huang S, Wang N, Xu Q, Xiong Q, Jing Y, Lv N, Wang L, Li Y, Yu L |
| Journal | LEUKEMIA & LYMPHOMA |
| Volume | 61 |
| Pagination | 1168-1177 |
| Date Published | APR 15 |
| Type of Article | Article |
| ISSN | 1042-8194 |
| Mots-clés | -X, 21) AML, 21)(q22, AML, Loss of X chromosome, q22), t(8 |
| Résumé | {The prognostic significance of loss of X chromosome (-X) in t(8;21) acute myeloid leukemia (AML) remains unclear. We evaluated the role of -X in 158 female patients with t(8;21) AML collected retrospectively from 15 Chinese AML study groups. Patients with -X accounted for 25.3% and showed a significantly higher complete remission rate, better 3-year cumulative incidence of relapse (25.2 vs. 50.5% |
| DOI | 10.1080/10428194.2019.1709836 |