Gender Differences in Idiopathic Pulmonary Fibrosis: Are Men and Women Equal?
| Affiliation auteurs | !!!! Error affiliation !!!! |
| Titre | Gender Differences in Idiopathic Pulmonary Fibrosis: Are Men and Women Equal? |
| Type de publication | Journal Article |
| Year of Publication | 2021 |
| Auteurs | Sese L, Nunes H, Cottin V, Israel-Biet D, Crestani B, Guillot-Dudoret S, Cadranel J, Wallaert B, Tazi A, Maitre B, Prevot G, Marchand-Adam S, Hirschi S, Dury S, Giraud V, Gondouin A, Bonniaud P, Traclet J, Juvin K, Borie R, Carton Z, Freynet O, Gille T, Planes C, Valeyre D, Uzunhan Y, Collaborators COFI |
| Journal | FRONTIERS IN MEDICINE |
| Volume | 8 |
| Pagination | 713698 |
| Date Published | AUG 5 |
| Type of Article | Article |
| Mots-clés | Gender differences, idiopathic pulmonary fibrosis, lung transplantation, occupational exposures, women |
| Résumé | {Background: Idiopathic pulmonary fibrosis (IPF) is characterized by a male predominance. The aim of the study was to explore gender differences in a well-designed French multicentre prospective IPF cohort (COhorte FIbrose, COFI) with a 5-year follow-up. Methods: Between 2007 and 2010, 236 patients with incident IPF were included in COFI. Gender characteristics were compared using a t-test, Chi-squared test and ANOVA, as appropriate. Survival analyses were performed. Results: Fifty-one (22%) females and 185 (78%) males with an average age at diagnosis of 70.1 +/- 9.20 and 67.4 +/- 10.9 years, respectively, were included in the cohort. Women were significantly less exposed to tobacco smoke [never n = 32 (62.7%) vs. n = 39 (21.1%), p < 0.001] and to occupational exposure [n = 7 (13.7%) vs. n = 63 (34.1%) |
| DOI | 10.3389/fmed.2021.713698 |