Baseline predictors for visual acuity loss during observation in diabetic macular oedema with good baseline visual acuity
| Affiliation auteurs | !!!! Error affiliation !!!! |
| Titre | Baseline predictors for visual acuity loss during observation in diabetic macular oedema with good baseline visual acuity |
| Type de publication | Journal Article |
| Year of Publication | 2020 |
| Auteurs | Busch C, Okada M, Zur D, Fraser-Bell S, Rodriguez-Valdes PJ, Cebeci Z, Lupidi M, Fung AT, Gabrielle P-H, Giancipoli E, Chaikitmongkol V, Lains I, Santos ARita, Kunavisarut P, Sala-Puigdollers A, Chhablani J, Ozimek M, Hilely A, Degenhardt V, Loewenstein A, Iglicki M, Rehak M |
| Journal | ACTA OPHTHALMOLOGICA |
| Volume | 98 |
| Pagination | E801-E806 |
| Date Published | NOV |
| Type of Article | Article |
| ISSN | 1755-375X |
| Mots-clés | diabetes, diabetic macular oedema, Diabetic retinopathy, Good visual acuity, Intravitreal therapy, macular oedema, Observation |
| Résumé | {Purpose To investigate clinical baseline characteristics and optical coherence tomography biomarkers predicting visual loss during observation in eyes with diabetic macular oedema (DMO) and good baseline visual acuity (VA). Methods A sub-analysis of a 12-month, retrospective study, including patients with baseline VA <= 0.1 logMAR (>= 20/25 Snellen) and centre-involving DMO. The primary outcome measure was the correlation between baseline characteristics and VA loss >= 10 letters during follow-up. Results A total of 249 eyes were included in the initial study, of which 147 eyes were observed and 80 eyes received anti-vascular endothelial growth factor (VEGF) treatment at baseline. Visual acuity (VA) loss >= 10 letters occurred in 21.8% (observed cohort) and in 24.3% (treated cohort), respectively. Within observed eyes, presence of hyperreflective foci [HRF; odds ratio (OR): 3.18 |
| DOI | 10.1111/aos.14390 |