Molecular markers of programmed cell death in donor hearts before transplantation

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TitreMolecular markers of programmed cell death in donor hearts before transplantation
Type de publicationJournal Article
Year of Publication2014
AuteursMarasco SF, Sheeran FL, Chaudhuri K, Vale M, Bailey M, Pepe S
JournalJOURNAL OF HEART AND LUNG TRANSPLANTATION
Volume33
Pagination185-193
Date PublishedFEB
Type of ArticleArticle
ISSN1053-2498
Mots-clésApoptosis, donation after circulatory death, donor heart, Heart transplantation, primary graft failure
Résumé

{BACKGROUND: In this study we investigate whether pro-apoptotic, pro-inflammatory and other early signaling markers indicative of increased propensity for cell death processes were evident in human donor heart allografts immediately before transplantation, and whether there is an association with primary graft failure. METHODS: A prospective study was performed utilizing donor left atrial myocardium collected at the time of implantation of hearts from brain-dead donors (BDD

DOI10.1016/j.healun.2013.10.013